Quantification of Optic Nerve Axon Loss Associated With a Relative Afferent Pupillary Defect in the Monkey
نویسندگان
چکیده
منابع مشابه
Quantification of optic nerve axon loss associated with a relative afferent pupillary defect in the monkey.
OBJECTIVE To quantify the amount of optic nerve axonal loss associated with the presence of a mild relative afferent pupillary defect (RAPD) in an experimental monkey model. METHODS The right macula of 5 rhesus monkeys (Macaca mulatta) was treated with concentrically enlarging diode laser burns until an RAPD was detected using a transilluminator light and measured with neutral density filters...
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PURPOSE To assess the amount of structural loss (retinal nerve fiber layer [RNFL] thickness loss, macular thickness [MT] and volume [MV] measured by optical coherence tomography [OCT]) and functional loss (visual acuity [VA], visual field mean deviation [MD], brightness sensitivity, and red perception) necessary for a relative afferent pupillary defect (RAPD) to manifest in patients with glauco...
متن کاملOrigin of the relative afferent pupillary defect in optic tract lesions.
OBJECTIVE To determine the percent decussation of pupil input fibers in humans and to explain the size and range of the log unit relative afferent pupillary defect (RAPD) in patients with optic tract lesions. DESIGN Experimental study. PARTICIPANTS AND CONTROLS Five patients with a unilateral optic tract lesion. METHODS The pupil response from light stimulation of the nasal hemifield, tem...
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Twenty-two patients with acute optic neuritis were studied by the techniques of infrared pupillometry and visual evoked responses (VER) to pattern reversal. A relative afferent pupillary defect was found in all cases and the magnitude of this defect was found to be related to the amplitude, but not to the latency, of the VER. During follow-up the afferent defect was found to remain persistently...
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PURPOSE The aim of this study was to compare the asymmetrical light reflex of the control subjects and patients with optic nerve disease and to evaluate the relationships among the relative afferent pupillary defect (RAPD), visual acuity (VA), central critical fusion frequency (CFF), ganglion cell complex thickness (GCCT), and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) using ...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2001
ISSN: 0003-9950
DOI: 10.1001/archopht.119.9.1333